Upfront Pharma

Fillerina 12 intensive filler grade 3

Fillerina 12 intensive filler grade 3
Fillerina 12 HA Densifying-Filler is the first dermo-cosmetic filler treatment to be used at home for external application. Shall be used every day for 14 days, in the morning or evening, depending on individual needs and habits. The application shall be performed by means of the special Dispenser/Applicator, which allows to draw up a specific amount of product and accurately release it onto those targeted areas such as age wrinkles and expression lines or onto cheekbones and lips to obtain more volume. Filler Effect for skin depressions, for the volume of cheekbones and lips Densifying Effect to support the skin firmness Intensive treatment in gel + nourishing film Intensive Treatment Fillerina 12HA Densifying-Filler features a mix of 12 different Hyaluronic Acid molecules with varying molecular weights and sizes that are especially effective at penetrating the layers of the skin (ex vivo tests with Franz Cells), thus allowing tissues to be filled in and plumped up. The molecular weights of the 12 Hyaluronic Acids with filling effect contained in this formulation range from 400 to 2000000 Dalton, and up to a Crosspolymer molecule, and all of them showed a great penetration capability (ex vivo test). Fillerina 12HA Densifying-Filler associates also 3 Collagen molecules with different molecular weights (2 000, 12 000 and 300 000 Da) which, by penetrating up to the dermis (ex vivo test with Franz Cells), can promote an increase in the extracellular matrix density and improve the filling effect, in synergy with Hyaluronic Acid molecules. With chronological ageing also the quantity and quality of Elastin, the protein that builds up elastic fibres, drastically decreases thus threatening skin plasticity and contributing to skin sagging. The formulation associates 2 molecules of Elastin with different molecular weights (1 400 Da and 2 200 Da), which aim at compensating this loss and restore skin elasticity and plasticity. Transdermic Technology The skin is hardly…

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